Why supplier selection is a workflow decision
I have watched a 2 mL autosampler vial ruin a $40,000 sequence. The vial was fine. The crimp was wrong. The aluminum seal sat at about 30 degrees off-axis, the septum puckered on one side, and the needle coring produced a sliver of silicone that plugged the column frit at injection 47. We lost the run, the column, and half a day. That experience shaped how I evaluate every vial supplier I have worked with since, and it is the reason this guide focuses on supplier selection as an operational...
